By: Masum Mahdy

In reply to Queda.

You may find this formula useful.
=SUM(FILTER(B2:S2,ISEVEN(COLUMN(B2:S2)))-FILTER(B2:S2,ISODD(COLUMN(B2:S2))))
Just instead of B2:S2, put your own cell range.
Regards
-ExcelDemy Team